Prohibition refers to the act of prohibiting a certain substance or act.

Prohibition may also refer to:

• Prohibition of alcohol, periods in several countries during which the manufacture, transportation, import, export, and sale of alcoholic beverages was or is restricted or illegal
  • Prohibitionism in Christianity
  • Prohibition in the United States
  • Prohibition in Canada
• Prohibition of drugs
  • War on Drugs, an American term commonly applied to a campaign of prohibition of drugs, military aid, and military intervention, with the stated aim being to reduce the illegal drug trade
• Prohibitionism in legal philosophy
• Prohibition sign ("no" symbol), a red circle with a diagonal line through it (running from top left to bottom right), covering a pictogram to indicate something is not permitted
• Prohibition (miniseries), a Ken Burns documentary on the American temperance movement and prohibition
• Writ of prohibition, in the United States, an official legal document drafted and issued by a supreme court or superior court to a judge presiding over a suit in an inferior court; the writ of prohibition mandates the inferior court to cease any action over the case because it may not fall within that inferior court's jurisdiction
• In the Quran, sura 66, At-Tahrim, is generally translated as "Prohibition"
• Prohibition (album), an album by French avant-garde singer Brigitte Fontaine